Found 157 of kd data for polymerid = 1494,1592 
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: <0.5nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 1.80nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding affinity to PKAalpha (unknown origin) using Lys-Arg-Thr-Leu-Arg-Arg as substrate after 8 mins in presence of [gamma-32P]ATP by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKd: 4.10nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 5.80nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 7.60nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 8.70nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 9.5nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 9.60nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 12.6nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 23nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 42nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged PRKACA expressed in baculovirus expression system using kemptide as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 52nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 56nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q25D8S70PubMedDrugBank
MMDB
PDB
3D Structure (crystal)TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 83nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 94nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 95.4nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 116nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged PRKACA expressed in baculovirus expression system using kemptide as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 247nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 249nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 319nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 443nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 594nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 600nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 720nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 720nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 720nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 1.64E+3nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 1.96E+3nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
Institute of Chemistry in Estonia
Institute of Chemistry in Estonia
Affinity DataKd: 2.18E+3nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to wild-type partial length human PKACalpha (G10 to F351 residues) expressed in bacterial expression system by Kinomescan assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to wild-type partial length human PKACalpha (G10 to F351 residues) expressed in bacterial expression system by Kinomescan assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
